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BioWorld Science

June 16, 2006

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Preliminary phase I data on KU-59436 reported at ASCO

New anticancer results of histone deacetylase inhibitors reported

Trials of mTOR inhibitors reported at ASCO meeting

Troxacitabine dosing optimized with adjustment for renal function

Davanat increases 5-fluorouracil exposure in mouse colon cancer model

Ceragenix compound significantly inhibits bladder cancer growth in vitro

Hemispherx completes design of Ampligen immunopotentiation trial

Medivir updates R&D progress

ViaCell enters into cardiac collaboration with Cordis

Phase III study of Transacin in PHN completes enrollment

Amylin and leptin interact synergistically to reduce body weight and fat levels in vivo

PRK-124 shows potential for aging skin and inflammatory skin disorders

Reducing PTP-1B expression with ISIS-113715 improves glucose control

Early graft function with PEG-encapsulated human islet allografts in patients with type 1 diabetes

Debiopharm and Sigma-tau sign agreement for istaroxime

Pharmos shareholders invited to vote on Vela acquisition

BioCryst and Green Cross enter South Korean agreement for peramivir

Merck KGaA agrees to sell stake in Schering AG to Bayer

Orphan drug status for glycopyrrolate to treat pediatric chronic drooling

Pfizer to license rights to Bayer's DGAT-1 inhibitors

Aida Pharmaceuticals expands drug development pipeline

ALGRX-4975 gives statistically significant pain reduction after knee replacement surgery

Class 1 review for Thelin complete response

FDA approval for Zelapar orally disintegrating tablets in Parkinson's

Dainippon Sumitomo Pharma launches AmBisome in Japan

Neoral approved in Japan for generalized severe myasthenia

Recent patents describe new agents for anxiety, sleep disorders, etc.

Recent NitroMed patent claims novel cardiovascular agents

New anticoagulants for treating thrombotic disorders reported in recent Lilly and Portola patents

Chimeric monoclonal antibody targeting EGFR well tolerated in clinical study

Ranirestat ameliorates diabetic neuropathy and cataract formation in rats

Preclinical findings on PC-DAC:Exendin-4 reported by ConjuChem

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