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BioWorld Science

Nov. 17, 2006

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Novel selective Aurora A kinase inhibitors developed at Cyclacel

Talotrexin pharmacokinetics determined in non-small lung cancer patients

Preclinical and phase I results reported for PTC-299

Bionomics reports recent progress

MorphoSys and Boehringer Ingelheim expand collaboration into cancer

Milestone in Nautilus and Creabilis Therapeutics' collaboration

Ono rounds up domestic and overseas developments

TAK-475 compared with and added to atorvastatin

D-4F improves HDL inflammatory function in coronary heart disease patients

DISPERSE studies show consistent platelet aggregation inhibition with AZD-6140

RSD-1235 effective in patients on rate- or rhythm-control medications

Darusentan lowers blood pressure in patients taking multiple therapies

Two-year study data show sustained benefit of abatacept in rheumatoid arthritis

Rheumatoid arthritis responses to golimumab maintained for 1 year

Oglufanide studied for hepatitis C in Australian trial

Fast track status for Ceflatonin in CML

ALTU-135 to begin phase III trial for cystic fibrosis in Q2 2007

Fast track designation for STA-4783 in metastatic melanoma

Recent patents disclose novel antiinfective agents

ALT-2074 reduces myocardial damage in diabetic mice

Agents for atherosclerosis, pulmonary hypertension patented

Pharmion acquires Cabrellis

Medivation outlines plans for key programs

Patents reveal novel agents for ulcer, inflammatory bowel disease, etc.

VEC-162 shows ability to induce and maintain sleep

ISA-247 shows good efficacy, maintains good kidney function in transplant patients

Vascugel is safe in phase I trials

Preclinical data on lead kinase compounds from SuperGen reported

Emerging companies showcased at BIO-Europe 2006: ACE BioSciences

Herceptin approved for adjuvant treatment of HER2+ node-positive breast cancer

Angiotech seeks CE Mark for Vascular Wrap product

Scientists track lung carcinogenesis in exhaled breath

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