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BioWorld Science

June 7, 2007

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Paroxetine does not significantly affect paliperidone pharmacokinetics

Novel oral CCK2 receptor antagonists profiled at Johnson & Johnson

Novel agents for treating endocrine-related disorders disclosed in recent patent literature

Novel therapeutic agents for respiratory disorders disclosed in recent Amira patent

New clinical data on aliskiren in hypertension

Metabasis presents preclinical results on its liver-targeted thyroid receptor agonist MB-07811

Rexin-G cleared for U.S. trials in breast cancer and sarcoma

France grants ATU for Thalidomide in elderly with untreated multiple myeloma

GSK's novel androgen receptor modulator improves muscle strength in orchidectomized animals

AstraZeneca completes successful tender offer for MedImmune shares

SPA agreement for pivotal study of Zybrestat in anaplastic thyroid cancer

Oral Hsp90 inhibitor SNX-5422 begins phase I trial

GlaxoSmithKline advances calcilytics program in osteoporosis

Transition Therapeutics acquires remaining shares of NeuroMedix

Constab's lead compound shows promise in metastatic colorectal cancer

Development activities continue for MK-2295

Corautus Genetics stockholders approve merger with VIA Pharmaceuticals

FDA places Telcyta trials on clinical hold

Pharmacokinetic, safety and efficacy data presented for PharmaMar's Zalypsis

STA-4783 + paclitaxel shows promise in metastatic melanoma

Vernakalant (iv) effective in conversion of atrial fibrillation in ACT 2 study

EVT-201 demonstrates robust effects on sleep onset and maintenance

Reolysin shows antitumor activity in advanced and metastatic cancers

Fractionated dose schedule and addition of methylphenidate reduces MLN-8054-related somnolence

Favorable interim results for Amgen anti-HGF antibody

R&D highlights from BIO 2007 in Boston: York Pharma

Doripenem filed for treatment of nosocomial pneumonia

Norditropin approved for short stature in children with Noonan syndrome

Altargo approved in E.U. for impetigo and other skin infections

Japanese launch for Somavert in acromegalia

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