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BioWorld Science

Oct. 8, 2007

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AstraZeneca identifies a novel class of small molecule UMP kinase inhibitors

Odanacatib's preclinical profile reported by Merck & Co.

Novexel's NXL-101 and NXL-104 evaluated in healthy volunteers

MK-0429 activity seen in animals and humans with bone metastases

Combination of CAPOX-B and cetuximab feasible in colorectal cancer

Studies provide data on S-013420 characteristics in vitro and in pneumonia patients

VIA receives financial support for ACS substudy of VIA-2291

First patient dosed in phase III trial of AGI-003 for IBS-D

Orexo adds two new projects to its development pipeline

FDA special protocol assessment assigned to atacicept pivotal trial

New renin inhibitor SPP-676 begins phase I clinical trials

Two phase II clinical trials launched for GFT-505

Positive phase II results reported for Lu-AA-21004 in major depression

Roche files a clinical trial application for Genmab antibody

Long-acting, nonopiate analgesic drug enters THA trial

Post-infarct cardiac healing of Corgentin to be evaluated in NIH trial

New agreement on development and commercialization of THR-174

Novel treatment options for obesity described in recent Servier and Pharmacopeia patents

New agents for treating gastrointestinal disorders reported in recent patents

Four phase I/II clinical trials commence for AEG-35156

Dosing begins in phase III registration studies for clevudine

Acusphere progresses toward NDA filing for Imagify

Enrollment commences for phase I 18F-AV-133 proof-of-concept study

MacroChem acquires rights to pexiganan

Ortho-Clinical Diagnostics introduces improved sensitivity troponin I assay

Phase I results reported for rabies antibody cocktail

New anticancer agents reported in recent patents

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