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BioWorld Science

Dec. 12, 2007

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Novel treatments for inflammatory disorders claimed in recent patents

Transdermal lisuride and oral ropinirole compared in restless legs syndrome trial

Study finds little effect of modafinil on fatigue related to Parkinson's disease

Phase I study of AMR-001 for myocardial infarction progresses

mAb-216 studied in B-lineage acute lymphoblastic leukemia patients

Bcr-Abl(T315I) drug-resistant clones are fully suppressed by combination therapy

Dainippon presents six-month ended September 30, 2007 results

Novel agents for gastrointestinal disorders reported in recent patents

FDA grants orphan drug designation to Celldex for CDX-110

Discovery of novel analgesic agents described in recent patent literature

Sequoia Pharmaceuticals submits IND application for SPI-452

Lexicon initiates phase IIa trial of LX-6171 for cognitive disorders

Speedel initiates phase IIa clinical trial of SPP-635 in diabetic patients with hypertension

DSMB recommends continuation of TRIST clinical trial of Oxford BioMedica's TroVax

Pfizer initiates phase I clinical trial of Rigel's R-343 for allergic asthma

Genmab initiates phase I/II study of HuMax-CD38 for multiple myeloma

Eisai acquires MGI Pharma for approximately USD 3.9 billion

FDA grants fast track designation to Osiris' Prochymal for acute GVHD

Novel V1a/V2 vasopressin receptor antagonist selected as a clinical candidate

Preclinical activity of OT-304 against chemotherapy-resistant tumors

Neurotrophic-expressing AAV vectors improve symptoms in mouse model of ALS

Mologen submits clinical study application for dSLIM for the treatment of cancer

Galapagos and GSK enter strategic alliance to develop novel antibacterials and antivirals

DOR BioPharma seeks approval for orBec NDA

ImmuPharma initiates phase IIb trials for IPP-201101 for systemic lupus erythematosus

Serenex initiates phase I trial of SNX-5422 for hematological malignancies

SymBio initiates phase II clinical study of bendamustine hydrochloride

FDA issues approvable letter for GSK's Requip XL for idiopathic Parkinson's disease

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