BioWorld Science

Aug. 18, 2008

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Amyloid-beta protein dimers identified as cause of synapse impairment

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Cara's peripherally active kappa opioid receptor agonist may be useful in treating visceral pain

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New antidiabetic compounds described in recent patents

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Effective antinociception without reward by novel endomorphin-1 analogue

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VAP-1 ligands for diagnosing inflammatory disorders claimed in recent patent

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Novel compounds with potential in the treatment of cancer disclosed

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Mu opiod receptor agonist AS-006 effective in rat model of osteoarthritic pain

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DiaMedica initiates enrollment in phase IIa clinical trial for DM-99 in type 2 diabetes

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FDA approves Gen-Probe's supplemental regulatory application for Procleix Ultrio in HBV

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SymBio and Eisai sign license agreement for bendamustine hydrochloride in Japan

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Spectrum launches Fusilev injection and files amendment to NDA for tablet formulation

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CV Therapeutics receives EMEA approval for Ranexa brand name

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Abbott and AstraZeneca enter nonexclusive U.S. marketing agreement for Crestor

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GTC and Ovation close agreement to develop and market ATryn in U.S

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Nutra Pharma reports safety data from phase IIb/IIIa clinical study of RPI-78M in AMN

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P-selectin inhibitor PSI-421 shows efficacy in models of vascular injury

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Antisoma reports survival data from phase II study of ASA-404 in prostate cancer

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FDA grants orphan drug designation to Santhera's omigapil in congenital muscular dystrophy

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OrthoLogic completes dosing for phase Ib human clinical trial of AZX-100 in scarring

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Seikagaku to initiate Japanese phase I clinical trial of CF-101 in rheumatoid arthritis

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FDA approves Prestwick's Xenazine for chorea associated with Huntington's disease

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Isis initiates phase I study of ISIS-353512 in healthy volunteers

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