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BioWorld Science

April 1, 2009

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Novel metabotropic glutamate receptor agonists display antiparkinsonian effects in vivo

Novel amide ketoacid-based inhibitors of HIV integrase show oral antiviral activity

Affitech shareholders approve proposed merger with Pharmexa

5-HT6 antagonist AVN-322 deemed a candidate for neurodegenerative diseases

Roche presents novel TAAR1 ligands

Novel metalloprotease inhibitors identified by Bracco

University of California, Oakland claims novel inhibitors of adenylosuccinate synthase

Novel triazole compounds claimed by Synta Pharmaceuticals

BPH symptom improvements with dutasteride-tamsulosin combination are clinically relevant

Herbal formula FAHF-2 effective in multiple food allergy model, safe in humans

Warner Chilcott has submitted an NDA to the FDA for low-dose oral contraceptive WC-3016

Small-molecule activator of cardiac myosin increases systolic function in stable heart failure

Sorafenib may alter ovarian function in women treated for renal cell carcinoma

GTC receives milestone from Lundbeck following FDA's approval of ATryn

Spaltudaq changes name to Theraclone and reports results from HIV antibody study

Detailed phase Ib results for antithrombotic Nanobody ALX-0081 reported by Ablynx

ExonHit expands neurological research activities to include epilepsy

Karo Bio reports positive results for KB-3305 in diabetes

Newron randomizes first patients in phase IIb/III ralfinamide study in pain

Early treatment with FX-06 and PCI affects outcomes in STEMI patients

Pharmasset commences first-in-human trial of its HCV inhibitor PSI-7851

SARcode reports phase I results for its ocular therapeutic, SAR-1118

Sepracor submits NDA to FDA for Stedesa as adjunctive epilepsy treatment

Shire and GlaxoSmithKline to co-promote Vyvanse for adult ADHD

Takeda submits NDA in Japan for Blopress/amlodipine besylate combination

Acorda Therapeutics receives FDA refuse to file letter for Fampridine-SR NDA

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