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BioWorld Science

May 20, 2009

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AT-7519 doses correlated with markers of CDK inhibition in solid tumor trial

PARP inhibition and antitumor activity seen with olaparib in phase I solid tumor study

PV-10 active as chemoablation in metastatic melanoma patients

OncoVEX(GM-CSF) active in unresectable metastatic melanoma

Discovery and development of PARP-1/2 inhibitor MK-4827 at Merck & Co. reported

Mutant FLT3 receptor inhibitor, ITRI-227, shows in vivo antitumor activity

Intrexon initiates phase Ib clinical trial of INcell-1001/AD-1001 in advanced melanoma

Takeda to acquire IDM Pharma in all-cash tender offer followed by merger

Northfield Laboratories to wind down business operations

MorphoSys and Daiichi Sankyo initiate two oncology-focused therapeutic antibody programs

OBT and GSK enter strategic alliance to develop cancer therapeutic antibodies

Asubio chooses Genedata's Expressionist to manage DNA array and molecular profiling data

FDA approves Johnson & Johnson's antipsychotic Risperdal Consta for bipolar I disorder

A.P. Pharma submits NDA to FDA for APF-530 in CINV

FDA accepts for filing MannKind's NDA for insulin product Afresa

Argenta elects drug to enter phase I studies under COPD collaboration with AstraZeneca

Clinical Data works with Dana-Farber Cancer Institute on FCGR3A gene variants

Shire presents guanfacine study results in ADHD

Novel mGluR5 receptor antagonists emerge from AstraZeneca R&D

Neurocrine reports results from Petal Study of elagolix for endometriosis pain

MUT-056399 targets Fabl enzyme for antistaphylococcal activity

Roche describes novel phosphatidylinositol 3-kinase inhibitors for cancer treatment

Exelixis claims the discovery of novel tropane compounds for cancer treatment

KBPA-101, a fully human antipseudomonas IgM, displays safety and tolerability in healthy volunteers

ZLB Plasma changes name to CSL Plasma

Mologen reports positive preliminary results from clinical trial with anticancer drug MGN-1703

Bayer receives Japanese approval for Nexavar for HCC

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