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BioWorld Science

June 8, 2009

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Astellas Pharma discloses TrkA tyrosine kinase inhibitors for the treatment of urinary conditions

Janssen describes prokineticin-1 receptor antagonists for the treatment of gastrointestinal diseases

Hsp27 inhibitor OGX-427 well tolerated, affects tumor markers in phase I study

AVI BioPharma and CFI sign additional drug development contract for AVI-5038 in DMD

Boehringer Ingelheim discovers phosphodiesterase 4B inhibitors for the treatment of COPD

DSMB recommends continuation of phase III trial comparing Avexa's ATC to 3TC in HIV

Novel sphingosine-1-phosphate receptor agonists described by Pfizer

Novel calcium channel blockers emerge from Pfizer R&D

Belatacept shows immunosuppressant activity in phase II/III studies in kidney transplant recipients

NIAID initiates trial evaluating AEOL-10150 for treating radiation exposure

EyeGate Pharma reports that EGP-437 improves signs and symptoms of dry eye

Pharming receives EMEA agreement on pediatric investigation plan for Rhucin

CNTO-328 shows acceptable safety and promising activity in phase II trials in CRPC and MM patients

Ancora receives phase I SBIR grant from NIH to research SMA vaccine

ACT signs exclusive license for anticancer therapeutic from University of Louisville

Cytopia completes 3-year research term under 2006 collaboration with Novartis

Somaxon resubmits NDA for insomnia drug Silenor to FDA

CDA-1 and CDB-1 show efficacy in phase II study in C. difficile diarrhea

Phase II data on olaparib in breast, ovarian cancer reported at ASCO

Single i.v. dose of BG-9928 displays minimal effect on cardiac conduction in healthy volunteers

Nebivolol does not affect hemoglobin levels in chronic heart failure patients; SENIORS data suggest

Rolofylline fails to demonstrate efficacy for acute heart failure in phase III PROTECT study

PolyMedix initiates dosing in second phase I systemic antibiotic trial

Anadys initiates strategic restructuring to focus on development of ANA-598 in hepatitis C

FDA grants orphan drug designation to Delcath's melphalan for neuroendocrine tumors

Lpath receives grant from the NCI to use for lead candidate Asonep

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