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BioWorld Science

May 11, 2010

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Cempra's Taksta for acute skin infections shows efficacy, tolerability in phase II trials

PRISM Biolab identifies novel Wnt signaling pathway inhibitors

Orchid Chemicals & Pharmaceuticals describes novel HDAC inhibitors

Novel nAChR alpha4beta2 ligands claimed by PsychoGenics and Illinois University

Novel "two-in-one" antibody targeting EGFR/HER3 shows preclinical potential

Prostate cancer diagnostic 99mTc-EC-0652 to proceed to phase 0 clinical evaluation

Intermune describes NS3/NS4 protease inhibitors

NeuroSearch claims nicotinic alpha7 receptor ligands

CTS-1027 well tolerated in HCV patients failing prior treatments

Evotec and Genentech enter agreement to discover small-molecule therapeutics

Optovue obtains FDA clearance for iVue SD-OCT

Japanese phase I CNS-7056 trial commences, triggering milestone for PAION

Nile completes dose escalation in phase II CD-NP study in heart failure

Cleveland BioLabs completes dosing in second safety study for CBLB-502

Wnt signaling inhibitor CW-232291 to advance to phase I

Phase I safety data reported for orphan drug QPI-1002

MediGene signs license agreements with GC-Rise and JS Bio for Veregen

Proof-of-concept study in irritable bowel disease encourages larger studies with AST-120

Phase III and other data on morphine/oxycodone combination reported

Humenza well tolerated and immunogenic in children

Takeda and Janssen Pharmaceutical agree to copromote Velcade in Japan

Novartis to begin phase III studies of QVA-149 combination therapy for COPD

FDA accepts review of sBLA to expand indication of Menveo in children

Generex achieves enrollment of over 400 subjects in Generex Oral-lyn study

Acrux and Vivus sign settlement agreement for Luramist dispute, Vivus license terminated

CrystalGenomics completes phase I SAD study of antibiotic candidate CG-400549

NexACT technology shown to enhance bioavailability of rituximab in preclinical study

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