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BioWorld Science

Feb. 18, 2011

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Phase I/II trial of mesenchymal stem cells for Crohn's disease-associated fistulas advances

Dopaminergic gene variations influence response to antipsychotics

New Toll-like receptor 7 agonist PF-4171455 selected for investigation for hepatitis C

Preclinical and clinical phase I data presented on THR-18 for stroke

Blood biomarkers can differentiate stroke and stroke-mimicking conditions

AstraZeneca's AZ-876 inhibits atherosclerosis and shows no inflammatory effects in vivo

Abbott updates highlights for fourth quarter of 2010

Threshold Pharma and FDA agree on SPA for phase III TH-302 trial in soft tissue sarcoma

Sanofi-aventis withdraws Anzemet for chemotherapy-induced nausea and vomiting

Pantarhei Bioscience seeks to acquire women's health activities from Organon

FDA approves aripiprazole for bipolar I disorder as an adjunct to mood stabilizers

Inspire Pharma discontinues development of denufosol for cystic fibrosis

DPZ and Ascenion sign license agreement for recombinant VP1-containing VLP

Acadra shows promise in phase I/IIa trial in chronic lymphocytic leukemia

Phase II trial of PXL-01 for prevention of postsurgical adhesions is extended to Germany

Novartis claims new inhibitors of serine/threonine-protein kinase D1

Dosing complete in phase I trial of HuCNS-SC in pediatric Pelizaeus-Merzbacher disease

Santhera regains rights to fipamezole from Biovail

Cytochroma begins phase IIb trial of CTAP-101 for vitamin D insufficiency in chronic kidney disease

Astellas' Protopic approved in Canada for prevention of eczema flares

Chimerix receives BARDA contract to develop CMX-001 for smallpox

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