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BioWorld Science

May 11, 2011

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Sanofi-aventis presents highlights of first quarter of 2011

Novel tetracycline TP-2758 efficacious in models of urinary tract infections and pyelonephritis

New nicotinic acetylcholine alpha7 receptor agonists claimed

Novel agents for Gram-negative bacterial infections synthesized at Pfizer

Merck & Co. patents new inhibitors of Mdm2-p53 interaction

Cephalon begins phase I/II CEP-9722 trial in advanced solid tumors

Albany Medical School and Aegis Therapeutics join to develop peptide against breast cancer

Evotec achieves new milestone in Boehringer Ingelheim drug discovery alliance

AstraZeneca discloses preclinical data on AZD-5363, in phase I testing in solid tumors

VT-1129 shows benefit in model of cryptococcal meningitis

Pooled trial data show linaclotide improves symptoms of constipation

AZD-2066 reduces transient lower esophageal sphincter relaxations in healthy subjects

Concert Pharmaceuticals prepares new GABA(A) receptor modulators

New sepiapterin reductase inhibitors claimed

Pharmacyclics discloses new tyrosine-protein kinase BTK inhibitors

Gentium submits defibrotide MAA to EMA for hepatic VOD in stem cell transplant recipients

Phase III trial of istradefylline in Parkinson's disease meets primary endpoint

Roche seeks FDA and EMA approval for vemurafenib in metastatic melanoma

National Cancer Institute to sponsor phase I study of Reolysin in multiple myeloma

Results from Asian study of lurasidone in schizophrenia inadequate to support filing in Japan

Sosei gains Japanese rights to antifungal agent Loramyc from BioAlliance

Allos Therapeutics and Mundipharma to codevelop anticancer drug Folotyn

Takeda acquires exclusive rights to fomepizole in Japan from Paladin Labs

Swissmedic approves Novartis' Votubia for brain tumors associated with tuberous sclerosis

Galapagos commences second proof-of-mechanism phase I trial of GLPG-0778

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