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BioWorld Science

July 4, 2011

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SELS gene SNPs linked to cardiovascular disease risk in patients with diabetes

DURATION-3 extension trial demonstrates long-term efficacy of weekly exenatide

Phase II data presented on CCX-140-B in type 2 diabetes

PAI-1 inhibitors TM-5275 and TM-5441 show promise to treat diabetic nephropathy

SRT-2104 exhibits anti-inflammatory activity in model of colitis

Novel fatty acid amide hydrolase 1 inhibitors reported

Novartis presents new lysophospholipid S1P1 receptor agonists

European Commission extends label for Avastin/Xeloda combination in metastatic breast cancer

Kyowa Hakko Kirin begins phase III trials of KW-3357 in DIC

Chugai obtains approval in Japan for use of Tarceva in pancreatic cancer

Abbott Japan and Eisai obtain Japanese approval for new indication and formulation of Humira

Tibotec and Gilead Sciences enter license agreement for fixed-dose antiretroviral combination tablet

AstraZeneca gains Japanese approval for proton pump inhibitor Nexium

Cellceutix applies for approval to begin clinical studies with anticancer compound Kevetrin

FDA committee recommends withdrawing approval for Avastin + paclitaxel in metastatic breast cancer

Ablynx begins phase I study of ALX-0651 for use in stem cell mobilization

First patient dosed in phase II part of talactoferrin OASIS trial in severe sepsis

DuPont patents new fatty-acid amide hydrolase 1 inhibitors for pain

Novel tyrosine inhibitors for skin disorders disclosed by Galderma

Panacea Biotec presents novel sodium/glucose cotransporter 2 inhibitors

Novogen discloses new agents for the treatment of cancer

Phase III study demonstrates safety and efficacy of Zertane in premature ejaculation

Novartis obtains approval in Japan for Onbrez inhalation capsules in COPD

Japanese MHLW approves Merck & Co.'s Gardasil, Zolinza and Cubicin

Oral anticoagulant Xarelto approved in U.S. for prophylaxis of deep vein thrombosis

FDA approves Novartis' once-daily bronchodilator Arcapta Neohaler for patients with COPD

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