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BioWorld Science

June 13, 2012

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SIRT1 activation investigated in models of obesity

Novel data reported on GKM-001 in diabetes and obesity

Phase I results encourage continued clinical evaluation of PEGylated C-peptide

First-in-human data disclosed on gene-modified T cells to facilitate stem cell transplants

Roche presents novel LRRK2 inhibitors

Bristol-Myers Squibb patents novel inhibitors of CYP17

Novel diagnostics disclosed by Janssen Pharmaceuticals

Merck & Co. reports new CGRP receptor antagonists

New PI3K inhibitors developed in U.S.

Synta Pharmaceuticals prepares new IL-2/CRAC-targeted products

Pharmanest launches phase II study of SHACT

Eltoprazine study in Parkinson's disease meets primary objective

Summit achieves milestone in development of SMT-C1100

Novel dipeptidyl peptidase IV inhibitor shows promise in diabetes/obesity models

Combination therapy shows surprising synergistic efficacy in Batten disease model

VaxInnate begins phase I H5N1 vaccine study

ImaginAb and BZL Biologics expand collaboration

Invega Sustenna formulation enters phase III trials

Greer reports data from phase III sublingual immunotherapy trial

Proof-of-concept study begins for Ampyra

Cempra starts phase II trial in gonococcal infections

Lead Tokai product receives FDA fast track status

Two first-in-class PolyMedix products receive approved generic names

Jazz Pharmaceuticals completes acquisition

FDA grants fast track status to synthetic ectodysplasin-A

Enrollment under way in NX-1207 trial in low-grade localized prostate cancer

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