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BioWorld Science

Aug. 25, 2014

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Combination of GPR40 agonist and GLP-1 agonist improves glucose control in type 2 diabetes

WNT-974, a porcupine inhibitor targeting Wnt signaling in clinical testing

Candidate antidepressant mGlu2 and 3 receptor antagonists identified at Lilly

Development of a mouse model mimicking human ulcerative colitis

Paradigm to conduct genomic analysis to predict response to Tesaro's TSR-011

NuSirt Biopharma initiates phase II study of metformin/leucine combinations

Cardiac-selective sodium current inhibitor discovered at Gilead Sciences

ENSPIRIT trial of custirsen passes interim futility analysis

Heptares uses StaR platform to derive orexin receptor antagonists

Antitope and University College London to generate fully humanized antibodies

AbbVie begins phase I study of ABT-957 in subjects with Alzheimer's disease

Genentech begins phase I study of MOXR-0916 in locally advanced or metastatic solid tumors

Novel anti-HCV MAbs disclosed by Genentech

Researchers in Japan disclose humanized anti-HMGB1 MAbs

FDA grants Insys Therapeutics' cannabidiol orphan drug designation for GBM

Advaxis and Merck & Co. to collaborate on cancer immunotherapy combination trial

Nuvilex's cancer treatment evaluated in preclinical studies for malignant ascites

Enrollment open in phase I study of CB-5083 for relapsed/refractory multiple myeloma

Stanford University begins first-in-human study of Hu5F9-G4 for solid tumors

Vertex patents novel Na channel modulators

Naurex designs a new series of NMDA receptor modulators

DeuteRx divulges new deuterated PPAR-gamma agonists

Latuda launched in the U.K. for schizophrenia

Phase III REGULATE-PCI of Revolixys Kit halted

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