Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 20, 2014

View Archived Issues

VU-0453595 shows potential for schizophrenia in a mouse model

Preliminary data on safety and efficacy of ALD-403 for the prevention of migraine

Protagen and Qiagen to develop protein-based companion diagnostics for autoimmune drugs

Maruho announces results of the phase III study of M-8010 for the treatment of psoriasis vulgaris

Theravectys updates on phase I/II trial of lentiviral vector HIV vaccine

Intellia Therapeutics closes financing to develop ex vivo gene therapies using CRISPR-Cas9 system

Preclinical data for an orally active opioid analgesic, SEO-16

Clinical benefit on rheumatoid arthritis demonstrated in phase I trial of FPA-008

Preliminary results of a phase II study comparing AQ-13 to coartemether

CYP7A1 inhibitor NGM-282: results of first phase I trial

Aldoxorubicin clinical trials placed on partial clinical hold

Spinal muscular atrophy program enters phase Ib/IIa trial

Health Canada clears Immunovaccine to conduct phase II trial of DPX-Survivac

Kissei Pharmaceutical submits NDA in Japan for PA-21

FDA grants orphan drug designation to Cabaletta for SCA3

Merrimack Pharmaceuticals receives FDA fast track designation for MM-398

Synergy Pharmaceuticals reports data from phase II SP-333 trial

Ajinomoto discloses new GS activators for diabetes

Merck & Co. patents novel MAPK 1 inhibitors for cancer

Vitae Pharmaceuticals patent reports new RORgamma inverse agonists

Janssen files NDA for 3-month formulation of paliperidone palmitate for schizophrenia

New compounds for bacterial infections designed by Neoculi

BerGenBio's BGB-324 receives FDA orphan drug designation

FDA awards breakthrough therapy designation to dupilumab for atopic dermatitis

Janssen files MAA for Simponi in severe active non-radiographic axial spondyloarthritis

Popular Stories

Today's news in brief
BioWorld
BioWorld briefs for Feb. 2, 2025.
Today's news in brief
Briefs
BioWorld MedTech briefs for Jan. 30, 2026.
Centessa’s CNT-9982 shows promise for MDD
BioWorld Science
Orexin OX2 receptor agonists have demonstrated the ability to enhance wakefulness in rodent models, as well as in nonhuman primates and patients with narcolepsy...
First-in-class ADC targeting DEM-TXX shows high preclinical efficacy
BioWorld Science
Researchers at DEM Biopharma Inc. reported preclinical findings demonstrating the efficacy of DEM-301, a bifunctional antibody-drug conjugate (ADC) engineered to...
5-HT2R allosteric ligands attenuate cocaine use and seeking behavior
BioWorld Science
Serotonergic G-protein-coupled receptors (GPCRs), including the 5-HT2A receptor (5-HT2AR) and 5-HT2CR, are key regulators of cortical signaling pathways and...