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BioWorld Science

June 9, 2015

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Novogen's brain tumor candidate TRXE-009 crosses BBB in animal studies

Vertex and Parion to develop ENaC inhibitors for cystic fibrosis and pulmonary diseases

R-Tech Ueno collaborates with Spanish institutions on new drug for cerebral infarction

BMS starts phase I/IIa trial of ADC in solid tumors

BeiGene initiates phase I study of BGB-A317 for advanced cancer

AYX-2 transcription factor decoy shows potential for the treatment of chronic pain

EC-1456 generally well tolerated in phase I trial

Regeneron advances two programs: REGN-475 and REGN-2222

Corcept Therapeutics patents GR modulators

Jazz Pharmaceuticals starts phase III program for JZP-110 in excessive daytime sleepiness

Actelion Pharmaceuticals reports TPH1 inhibitors

CRT and ICR scientists develop Raf kinase B inhibitors

Phase I data reported for angiogenesis inhibitor TAS-115

Pivotal Therapeutics starts phase IIa trial of omega-3 fatty acid therapy

Neurocrine Biosciences suspends two planned trials of NBI-77860

Lilly reports first human data for Notch signaling inhibitor LY-3039478

Global Blood Therapeutics reports Hb allosteric modulators

PlasmaTech obtains license to AAV gene therapy for juvenile Batten disease

BioMarin files for European approval of drisapersen for DMD

NCI selects Rexahn's RX-21101 for preclinical characterization program

Idera and MD Anderson collaborate to conduct trials of intratumoral IMO-2125

Probuphine noninferior to sublingual buprenorphine in phase III trial in opioid dependence

PNP Therapeutics gene-directed enzyme prodrug therapy granted FDA orphan designation

DalCor and Montreal Heart Institute to collaborate on phase III trial of dalcetrapib

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