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BioWorld Science

Dec. 17, 2015

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Combination of three approved beta-lactams kills MRSA

Idera Pharmaceuticals begins phase I/II trial of intratumoral IMO-2125

Solgenix initiates pivotal phase III study of SGX-301 for CTCL

FDA grants orphan drug designation to AAV9-IDS for the treatment of MPS type II

Nemucore Medical Innovations forms licensing agreement with Pfenex

Poxel confirms start of phase IIb study in Japan

Attempts to model ALS in transgenic mice expressing C9orf72 containing hexanucleotide repeats

Carmot and Sunesis present PDK1 inhibitors

Lilly reports AMPA receptor antagonists

Medivation introduces bromodomain-containing protein inhibitors

BET inhibitor from Zenith Epigenetics shows efficacy in preclinical studies

PI3Kgamma inhibitor BVD-723 shows activity in murine models of cancer

Probody drug conjugate targeting CD166 shows promise for the treatment of cancer

CC-31244 shows potent anti-HCV activity

Sanofi and Boehringer Ingelheim propose exchange of business units

GBT-1118 improves hypoxia survival in mice

Novartis patents nonsense mutation suppressors

Universidad de Granada and Universita degli Studi di Padova disclose choline kinase inhibitors

Pharmakea announces USP9X inhibitors

Taiho Pharmaceutical reports AR antagonists

DNDi criticizes KaloBios plan to register benznidazole for Chagas disease in the U.S.

Arch Therapeutics reports preclinical data for hemostatic; cleared to start clinical trial in Europe

Validus acquires U.S. rights to several launched products from Sanofi

AstraZeneca forms strategic alliance with WuXi AppTec and expands Chinese operations

AstraZeneca acquires majority stake in Acerta Pharma

Viekirax filed for additional indication in Japan

FDA accepts BLA for PaxVax's oral cholera vaccine Vaxchora

FDA lifts clinical hold on Advaxis cancer vaccines

Galapagos and Gilead Sciences partner to develop filgotinib for inflammatory diseases

FDA grants fast track designation to ibudilast for ALS

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