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BioWorld Science

April 18, 2017

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Phase I/II results for olaparib plus temozolomide in small cell lung cancer

FDA issues complete response letter for baricitinib for moderate to severe rheumatoid arthritis

Discovery of novel potent and selective EphA4 agonists for the treatment of ALS

Icon Bioscience submits NDA for Dexycu to treat inflammation associated with cataract surgery

Oxandrolone induces early puberty in boys with Klinefelter syndrome

Rigel submits NDA for fostamatinib for chronic ITP

First-in-human phase I results for YS-110 in advanced CD26-expressing cancers

FDA grants breakthrough therapy and RMAT designations to RVT-802

FDA grants accelerated approval to Tecentriq for bladder cancer not treatable with cisplatin

ECBI-11 has novel mechanism for disrupting estrogen receptor 1 signaling in breast cancer

Bristol-Myers Squibb licenses compounds to Biogen and Roche

Amarantus Bioscience creates new subsidiaries Elto Pharma and MANF Therapeutics

FDA awards fast track designation to Relmada's d-methadone for major depressive disorder

Interim results from phase III HAVEN 2 pediatric trial of emicizumab in hemophilia A

Sun Pharma Advanced Research discovers estrogen receptor antagonists

Bayer Pharma discloses tankyrase-1 and tankyrase-2 inhibitors

Shingrix submitted for regulatory review in Japan

FDA breakthrough therapy designation granted to CTL-019 for adults with DLBCL

Astex and Cancer Research Technology identify Hdm2-p53 interaction inhibitors

Motif Bio reports promising topline results from REVIVE-1 trial of icalprim in ABSSSI

Abide Therapeutics presents Lp-PLA2 and ABHD6 inhibitors

Faron collaborates with University of Birmingham on clinical trial of Clevegen

Amgen describes activity of first-in-class Mcl-1 inhibitor AMG-176

Universite Paris-Est Creteil Val de Marne, INSERM and CNRS patent heme oxygenase activators

AmpliPhi receives positive feedback from FDA on phase II trial plans for AB-SA01

HitGen and Pfizer collaborate to build and screen novel DNA-encoded libraries

Cleveland BioLabs updates entolimod progress