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BioWorld Science

June 12, 2018

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FDA grants orphan drug designation to LK-01 for the treatment of AML

XORTX files FDA pre-IND meeting request letter

New Dong-A compound shows activity against resistant Gram-negative bacteria

HIV-1 fusion peptide targeting, a promising vaccination strategy eliciting neutralizing antibodies

Phase III study of Vical's HSV-2 therapeutic vaccine does not meet primary endpoint

Preliminary data presented from interim review of phase I/II study of OXS-1550

Atogepant demonstrates efficacy and safety in phase IIb/III study in episodic migraine

FDA grants fast track designation to Betalutin for relapsed or refractory follicular lymphoma

Significant improvements in ulcerative colitis seen with apremilast in phase II trial

Boehringer Ingelheim initiates phase I study of BI-907828 in solid tumors

Phase III data support ibrutinib/rituximab combination in Waldenstrom's macroglobulinemia

Lilly and AstraZeneca discontinue phase III trials of lanabecestat for Alzheimer's disease

Merck KGaA reports promising phase II data for tepotinib in advanced HCC

EMA grants PRIME designation for Themis' Chikungunya vaccine

First-in-human data on FDL-176 in healthy subjects presented

NeuroRx completes phase IIb/III feasibility enrollment for NRX-101 in suicidal bipolar depression

Merck & Co. patents DGAT2 inhibitors

Arcus Biosciences presents CD73 inhibitors

FDA clears Arcus' INDs for AB-928 and AB-122

Retrotope begins compassionate use trials of RT-001

Aquinox initiates phase II study of rosiptor in chronic prostatitis/chronic pelvic pain syndrome

Takeda launches Azilect in Japan for Parkinson's disease

Apabetalone reverses HIV-1 latency and induces apoptosis of reservoir cells

New nonhuman primate model allows testing of antifibrotic therapeutic candidates

Cancer Research UK advances AST-VAC2 into phase I trial for NSCLC

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