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BioWorld Science

June 22, 2018

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FDA grants QIDP designation to ACX-362E to treat C. difficile infection

Metastatic breast cancer regression by immunotherapy with TILs enriched for neoantigen reactivity

PTC Therapeutics presents updated preliminary data from FIREFISH

Reata initiates first-in-human study with allosteric RORgammat inhibitor RTA-1701

Preliminary data presented from first-in-human phase I trial on MTL-CEBPA

First-in-human data presented for novel monoclonal anti-IL-6R-alpha antibody BCD-089

HTX-011 receives breakthrough therapy designation and reaches primary endpoint in phase IIb studies

Researchers present primary efficacy data on PRO-140 from CD02 study

MaaT Pharma enters agreement for GvHD microbiome therapy

New dUTPase inhibitors synthesized at CV6 Therapeutics

Bristol-Myers Squibb describes glycogen synthase kinase 3 inhibitors

Dual MetAP 2/DPP-IV inhibitors identified at Lilly

Statins improve venetoclax anticancer activity in hematologic malignancies

FDA grants regenerative medicine advanced therapy designation for VY-AADC

Alpha Biopharma closes series A financing for phase II study of AZD-3759

ACKR3 gene copy number variations linked to pregnancy loss

Ironwood initiates phase III trials of IW-3718 in persistent GERD

Attenuated vaccine candidate shows rapid probiotic-like protection from cholera in animal models

Revance initiates phase III program with RT-002 injectable for cervical dystonia

FDA accepts sBLA for Opdivo plus low-dose Yervoy for first-line NSCLC

Phase II/III trial of NBTXR-3 in soft tissue sarcoma meets primary endpoint

Synairgen reports interim data from phase II trial of SNG-001 in COPD

Takeda acquires control of TiGenix

REACH1 study of ruxolitinib in steroid-refractory acute GvHD meets primary endpoint

FDA accepts IND for lanifibranor in patients with type 2 diabetes and NAFLD

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