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BioWorld Science

June 27, 2018

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Akero Therapeutics closes series A financing to advance development of AKR-001

aTyr Pharma presents positive phase I results for ATYR-1923

Prespecified efficacy endpoint met in phase II study of bemcentinib plus Keytruda in NSCLC

CHMP adopts positive trend vote recommending the approval of the MAA for neratinib

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Navitor Pharmaceuticals initiates phase I trial of NV-5138 for treatment-resistant depression

Safety and immunogenicity of ZMapp antibody cocktail for Ebola virus tested in healthy adults

First-in-human data reported for AMV-564 in patients with relapsed/refractory AML

Stemline Therapeutics completes rolling BLA submission to the FDA for Elzonris

Phase II results for CLT-008 in patients receiving AML induction therapy

Increasing the sensitivity of mu-opioid receptors

Enteris reports results from final arm of phase IIa trial of Ovarest

Safety and efficacy of anti-PD-1 antibody SHR-1210 plus apatinib in refractory HCC, GC and EGJC

Phase II trial evaluates antimalarial activity of single-dose DSM-265

FDA approves Zemdri for cUTI, but issues CRL for bloodstream infections

In vivo evaluation of PD-L1-targeted PET imaging agent [64Cu]DK222

Chugai describes OWL-833, an orally active non-peptide GLP-1 receptor agonist

Apellis initiates phase III trial of APL-2 in PNH

Arcus Biosciences, Infinity Pharmaceuticals collaborate on studies of triple combination therapies

Fraunhofer-Gesellschaft describes new bacterial glutaminyl cyclase inhibitors

Ensemble Therapeutics divulges IDO-1 inhibitors

Aclaris initiates phase II trial of ATI-501 for alopecia totalis and alopecia universalis

Pivot plans IND filing to begin clinical trials with PVT-005

FDA advisory committees recommend against approval of Remoxy ER

Servier and Galapagos initiate phase II trial with S-201086 in osteoarthritis

ThromboGenics plans to change name to Oxurion

Summit discontinues development of ezutromid based on results of PhaseOut DMD trial

Phase III trial of rosiptor in interstitial cystitis/bladder pain syndrome misses primary endpoint

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