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Home » Newsletters » BioWorld Science

BioWorld Science

July 31, 2018

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Sleep is depression's opposite

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Novel CRISPR/Cas-mediated rat model of idiosyncratic drug-induced liver injury

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First-in-human data presented for AB-023

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Aspirin increases lysosomal biogenesis via PPARalpha and decreases amyloid plaque pathology in mice

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Motile sperm domain-containing protein 2 promotes breast cancer cell migration and metastasis

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Estrogen receptor alpha activation depends on fibronectin-beta1-integrin pathway in breast cancer

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Bench and bedside: Phosphatase inhibition sheds ugly duckling status with new platform technology

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Beta Cat studies BC-2059 for unresectable desmoid tumors in phase I

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Primary endpoints met in phase IIb study of PRX for presbyopia

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Phase III study of RHB-104 in Crohn's disease meets primary endpoint

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Regenera initiates phase II study of RPh-201 in NAION

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Dong-A conducts phase II study with DA-8010 in overactive bladder

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First-in-human study investigates CALR exon 9 mutant peptide vaccine in CALR-mutant MPNs

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Janssen studies PRMT5 inhibitor JNJ-64619178 in advanced cancers

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FDA approves Azedra for pheochromocytoma or paraganglioma

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Arcus cleared to begin phase I trial of anti-TIGIT antibody AB-154

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Stop-gain variant in GMIP gene tied to Alzheimer's disease pathogenesis

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Contactin-2 levels are altered in mild cognitive impairment

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ASTRAL-1 study of guadecitabine in AML does not meet coprimary endpoints

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Immutep to begin phase II study of eftilagimod alfa with pembrolizumab

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Regeneus reports promising first-in-human data for autologous tumor vaccine RGSH-4-K

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Phase II study of laquinimod in Huntington's disease does not meet primary endpoint

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European Commission approves Aimovig to prevent migraines

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HSP27 found as a potential therapeutic target for treating VCID

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