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BioWorld Science

Aug. 24, 2018

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Gene therapy for dominant blindness

Wee1 is a target in rhabdomyosarcoma

KW-6356 affects motor scores in phase II early Parkinson's disease trial

Liver-targeted prodrug may prove effective in fibrosis

DA-9701 may improve gastric motility in Parkinson's disease patients

Amgen targets the apelin receptor with AMG-986 for heart failure therapy

Lenvima approved in Europe as first-line treatment in adults with advanced or unresectable HCC

Toca 5 pivotal phase III study of Toca-511/Toca-FC continues without modification

Preclinical data and structure described for next-generation TYK2 inhibitor PF-06826647

GlaxoSmithKline presents leucine-rich repeat serine/threonine-protein kinase 2 inhibitors

Yangzhou Blue Biomedical Technology Co. patents penicilone derivatives

N-acetyl-beta-D-glucosaminidase inhibitors identified at Janssen

University of South Australia discloses cyclin-dependent kinase inhibitors

New selective Mcl-1 inhibitors with in vivo activity described by Vanderbilt University

DSMB completes new review of safety data from FOCUS trial of melphalan/HDS

FDA approves Takhzyro for prevention of HAE attacks

FDA approves Diacomit for seizures associated with Dravet syndrome

Telix submits CTA to begin phase III trial in Europe with TLX-250 for renal cancer imaging

FDA approves Inveltys for post-operative inflammation and pain

bluebird bio and Gritstone Oncology establish cancer cell therapy collaboration

FDA approves cobas EGFR Mutation Test v2 as companion diagnostic test with Iressa

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