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BioWorld Science

Sep. 10, 2018

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Optimized 1,4-oxazine BACE1 inhibitor shows improved safety profile in preclinical studies

When a bear spits in the woods

Microbiome metabolites and host responses

Neutrophil-lookalike membranes fight arthritis

Host changes after Zika virus infection

Carbon dioxide aggravates COPD

Different vaccination routes lead to different protection

Sichuan Kelun-Biotech Biopharmaceutical divulges MAP3K5 inhibitors

Korean researchers synthesize new LRRK2 inhibitors

Daiichi Sankyo discovers bacterial tryptophanase inhibitors

Domainex patents new IKK-E, TBK1 and SIK2 kinase inhibitors

New model of thrombopoietin receptor activation in myeloproliferative neoplams

Small-molecule CNS-penetrant autophagy enhancers suitable for study in vivo identified

Within patients, untreated metastases largely share drivers

BDD and Cingulate complete license agreement with OralogiK-enabled triple pulse products

Oryzon receives approval to initiate phase IIa REIMAGINE study of vafidemstat in aggressiveness

ZNF281 inhibits neuronal differentiation and predicts the prognosis of neuroblastoma

CureDuchenne invests in 4D Molecular Therapeutics

FDA issues complete response letter for mepolizumab in COPD

Grifols signs agreement to support research in rare and chronic diseases

Roche opens enrollment in phase III study of RO-6867461 for DME

Sareum selects SDC-1801 from TYK2 inhibitor program for advancement in autoimmune diseases

AstraZeneca initiates first-in-human study of AZD-8233

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