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BioWorld Science

Sep. 21, 2018

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Phase I trial explores cellular adoptive immunotherapy in sarcoma

ADAMTS18 found behind alveolar dysplasia and lung morphology

Nanotech-enabled mRNA delivery reactivates tumor suppressor

Vaspin shows cardioprotective effect in myocardial ischemia/reperfusion injury animal models

Treatment with the novel GPR88 agonist RTI-13951-33 reduces alcohol intake in vivo

QCA-570 demonstrates efficacy and safety in preclinical leukemia models

National Institute of Biomedical Innovation and Biken synthesize lipid A adjuvant

Pharming receives complete response letter from FDA for Ruconest

Hadasit Medical Research Services and Development, Ramot patent glycogen synthase inhibitors

Jiangsu Hansoh Pharmaceutical Group, Shanghai Hansoh Biomedical discover MAP3K5 inhibitors

Global phase III ALPS study of roxadustat meets primary endpoints

Hulio, a biosimilar to adalimumab, receives marketing authorization in Europe

IRLAB announces updates to its pipeline

PET tracer for renal imaging tested in vivo

First patient treated in phase I trial of BAY-1905254

First patient enrolled in phase IIa HIV study of GnRH agonist ISR-048

Further studies planned after first-in-human trial of respiratory disease candidate OATD-01

FDA accepts Cardurion's IND for phase I study of CRD-733

New OTC-deficient pig model of metabolic liver disease developed

Mesoblast reports survival outcomes through day 180 in phase III study of remestemcel-L

European Commission approves Braftovi with Mektovi for advanced melanoma with BRAFV600 mutation

Galectin Therapeutics reports preliminary phase Ib data on GR-MD-02 in advanced melanoma

Plasma NfL and CSF biomarkers for the diagnosis of AD in adults with Down syndrome

Lorlatinib receives first approval in Japan

Viruses use Treacle to make host cells more hospitable

Sihuan begins phase II study of benapenem

Cyp8b1 silencing improves nonalcoholic fatty liver disease in mice by remodeling the bile acid pool

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