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BioWorld - Thursday, April 25, 2024
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BioWorld Science
Sep. 25, 2018
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Repurposed antifungal may be therapy for rare blood disorder
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New rat model of glutaric aciduria type I confirms cerebral ammonium accumulation
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Phase I trial explores AMG-510 for solid tumors with KRAS p.G12C mutation
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TREM-1 activation may alleviate development of neonatal bronchopulmonary dysplasia
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Panic-prone states facilitate fear by reducing mGlu2 function within the amygdala network
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Inhibitors of stromal p38MAPK/MK2 limit breast cancer metastasis and prevent bone loss
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Gene therapy for cocaine addiction
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Skeletal stem cell identified
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AAV-mediated gene transfer of scFvs shows viability for treatment of methamphetamine abuse in mice
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Thiomannosides, new oral FimH inhibitors for the treatment of urinary tract infections
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ASTRID study of enobosarm does not achieve statistical significance on the primary endpoint
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Eybelis granted marketing approval for glaucoma and ocular hypertension in Japan
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Beova granted marketing approval in Japan for overactive bladder
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Xospata approved in Japan for FLT3 mutation-positive relapsed or refractory AML
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PhaseBio reports promising phase I results with ticagrelor reversal agent PB-2452
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FDA lifts clinical hold for Sarepta's DMD micro-dystrophin gene therapy program
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Ovid initiates phase II studies of OV-935 for rare epilepsies
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AnaptysBio reports promising topline proof-of-concept data on etokimab in severe eosinophilic asthma
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New PKU mouse model developed
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FDA lifts partial clinical hold on tazemetostat trials
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Imfinzi approved in E.U. for locally advanced, unresectable NSCLC
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Phase IIa trial of EPI-589 in ALS shows improvement in CSF and plasma-based biomarkers
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FDA grants approval for Copiktra for CLL/SLL, accelerated approval in follicular lymphoma
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Japanese approval for Jivi for hemophilia A
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Pharmaxis synthesizes new LOX inhibitors
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First patient enrolled in phase I study of THR-687 for the treatment of diabetic macular edema
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Phase III trial of Soliris in neuromyelitis optica spectrum disorder meets primary endpoint
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Japanese approval for Blincyto for relapsed or refractory B-cell ALL
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Statistically significant reduction in abdominal pain seen in phase IIa study of olorinab
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Catabasis initiates phase III trial of edasalonexent for Duchenne muscular dystrophy
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