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BioWorld Science

Oct. 11, 2018

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Cleaning up synuclein

Crystal structure of Pseudomonas exotoxins and human 14-3-3 protein identifies a new target

ASM opens BBB in aging

Preclinical results presented for novel 6-amino-6-deoxy paramylon for the treatment of obesity

Novel anti-inflammatory CXCL12 neutraligand with improved characteristics discovered

Nilvadipine does not demonstrate efficacy in patients with mild to moderate Alzheimer's disease

Novel Janssen hepatitis B virus capsid assembly modulators possess potent antiviral activity

Hemispherx and Roswell Park enter clinical trial agreement to study Ampligen

U.S. DoD funding phase II combination study of TPIV-110 in breast cancer

Helix BioPharma, Moffitt Cancer Center expand collaboration

The nitty gritty: Drilling down into sepsis shows routes to treatment

Urinary exosomal CCL-21 mRNA as marker of histological injury and renal function deterioration in DN

PF-06939926 induces a greater amelioration of DMD pathology when administered at a younger age

GS-6207 shows long-acting nonclinical pharmacokinetic profile

R-DMDdel52, a new rat model of Duchenne muscular dystrophy, developed

Hypermethylation of miR-145-5p drives laryngeal squamous cell carcinoma invasion and metastasis

Chinese researchers patent adenosine A2A receptor antagonists

Gedeon Richter presents GABA-B receptor PAMs

New phase II/III trial in Brazil studies meningococcus C vaccine MenCC-Bio

Genentech and Roche identify MAP4K1 inhibitors

Cognition Therapeutics begins phase II trial of CT-1812 in mild to moderate Alzheimer's disease

Cardio Therapeutics patent describes PCSK9 inhibitors

Galera initiates phase III study of GC-4419 to reduce radiation-induced oral mucositis

Athenex discloses CRAC modulators as IL-2 production inhibitors

Perjeta approved in Japan for neoadjuvant and adjuvant use in HER2-positive early breast cancer

ASSESS trial demonstrates superior efficacy of Gilenya over Copaxone in relapsing-remitting MS

Ritter presents additional phase IIb data on RP-G28 for treatment of lactose intolerance

Stelara induces clinical remission and response in moderate to severe ulcerative colitis

Pharmaxis reports phase I data for first LOXL2 inhibitor

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