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BioWorld Science

Oct. 25, 2018

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Metabolic remodeling seen during liver regeneration

New Tau tracer [18F]S16 distinguishes patients with Alzheimer's disease from healthy controls

Long noncoding RNA CALM3-AS1 acts as a microRNA sponge to promote bladder cancer progression

Metastasis and self-renewal of group 3 medulloblastomas is driven by NOTCH1

DeltaNp63 promotes metastasis in triple-negative breast cancer

Exome sequencing reveals SLC20A1 to be a possible cause of cloacal and bladder exstrophy

Familial association of a variant in MEGF6 with osteoporosis

MDM2/p53 inhibitor PM-2 can radiosensitize p53-expressing tumors

AQP9 emerges as a candidate gene for keloid development

Results from the phase IIb RISE-SSc study of riociguat presented

Oyster Point's OC-01 and OC-02 demonstrate improvement in Schirmer's score for dry eye disease

China NMPA accepts NDA for zanubrutinib in relapsed/refractory CLL/SLL

Phase IIb study of SM-04690 in knee osteoarthritis meets primary endpoints

Takeda Pharmaceutical identifies GPR6 receptor modulators

Roche and Genentech patent new MAP4K1 inhibitors

Alexion and Dicerna collaborate on RNAi therapies for complement-mediated diseases

Inventiva synthesizes YAP-TEAD interaction inhibitors

Kyoto Pharmaceutical Industries divulges nonsense mutation suppressors

Janssen and collaborator present new antiviral compounds

Pfizer opens phase I study of PF-06952229 for advanced solid tumors

Syntrix enrolling patients for phase II trial of Omnitram for diabetic neuropathy

Privo opens phase I/II trial of PRV-111 for early-stage oral cancer

FDA approves Xofluza for influenza

First patient dosed in study of AXO-Lenti-PD gene therapy for Parkinson's disease

Growth hormone deficiency caused by homozygous GH1 deletion

Whole exome sequencing of Tunisian patients with ataxia further expands the known causative genes

Confirmatory phase III study of Talicia for H. pylori infection completes final patient assessment

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