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BioWorld Science

Oct. 29, 2018

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MedImmune initiates phase I study of MEDI-6570

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89Bio launches to develop drug for NASH

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France becomes first country to market baclofen preparation to reduce alcohol consumption

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Boehringer Ingelheim initiates phase I study of BI-730460

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Uniparental mice give insights into ESC imprinting

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Dual ICOS/CD28 antagonist demonstrates efficacy in models of autoimmune disease

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Single locus near SIM1 gene significantly associated with risk of erectile dysfunction

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OT-1096, a novel immunoactivating molecule that shows efficacy in xenograft models of TNBC

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Phase I U.S. data presented for KN-035 in patients with advanced solid tumors

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Pfizer and Novartis collaborate to study NASH therapy combinations

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ASP-5094 safe and well tolerated in patients with rheumatoid arthritis on methotrexate

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Griffithsin intravaginal gel well tolerated in first-in-human trial

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Opthea reports promising 12-week data from phase Ib study of OPT-302 in DME

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Novo Nordisk reports PIONEER 8 topline results with oral semaglutide in type 2 diabetes

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Phase II data presented for SEL-212 in symptomatic gout patients

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Novartis reports year 2 data from brolucizumab phase III trials in wet AMD

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Genentech presents data on faricimab and ranibizumab PDS in wet AMD

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Aduro initiates phase I study of ADU-1604 in metastatic melanoma

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New phase I trial evaluates TAK-981 in metastatic solid tumors or lymphomas

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Qrumpharma develops inhaled agent for nontuberculous mycobacterial infections

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Innovate demonstrates preclinical proof of concept for larazotide in NASH mouse model

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New phase Ib/IIa study explores use of AG-019 for treatment of early-onset type 1 diabetes

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