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BioWorld - Thursday, December 25, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 16, 2018

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Blocking complement protects synapses in AD

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Critical protein for intracellular antigen recognition is found

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AWOL cGAS is novel DNA repair player

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Alize Pharma 3 describes its first two assets

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Rafael opens phase III study of CPI-613 + mFolfirinox in metastatic adenocarcinoma of the pancreas

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Fas-immunomodulatory fusion protein potentiates efficacy of T-cell therapy in ovarian tumor model

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Tesaro presents phase I data from AMBER study of TSR-022 plus TSR-042

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AO-176, a novel anti-CD47 monoclonal antibody with a unique killing profile

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Microbiota mediate metformin clinical benefits

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Selective beta3-adrenoceptor antagonist APD-418 beneficial in heart failure models

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Nanjing TransThera Biosciences divulges IDO-1 inhibitors

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New compounds for helminthic infections discovered at Bayer Animal Health

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Novartis patents HBsAG secretion inhibitors

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Adynxx and twoXAR aim to discover new treatments for endometriosis

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OncoTartis divulges compounds for leukemias with MLL gene translocations

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Boehringer and Epizyme collaborate to develop novel epigenetic oncology therapies

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Cocrystal Pharma generates new influenza polymerase basic protein 2 inhibitors

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Amgen initiates first-in-human study of AMG-562

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Indoleamine 2,3-dioxygenase 1 inhibitors patented by Alberta Research Chemicals

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Baicalein regulates proliferation and chemosensitivity in HCC by upregulating miR-181a-5p

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Isofol initiates pivotal phase III study of arfolitixorin in metastatic colorectal cancer

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BO-264 is a potent and selective TACC3 inhibitor for the treatment of breast cancer

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Phase III trial of fruquintinib in third-line NSCLC does not meet primary endpoint of OS

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New AR degrader ARD-61 demonstrates efficacy in models of castration-resistant prostate cancer

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AstraZeneca reports final OS results from MYSTIC trial of Imfinzi in stage IV NSCLC

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uniQure reports initial phase IIb data on AMT-061 for hemophilia B

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Biohaven initiates phase III trial of rimegepant for preventive treatment of migraine

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Apolipoprotein D as a potential new target in Niemann-Pick type A disease

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PsiOxus and Parker Institute collaborate on virus-based gene therapy to treat solid tumors

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