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BioWorld Science

Nov. 19, 2018

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Kiss of death: tumor cells suck calcium from bone cells to metastasize

Data presented on BRM-inhibiting ureas as potential anticancer agents

Phase II trial explores whether EDP-1503 enhances response to pembrolizumab in advanced melanoma

PDE9 inhibition with CRD-733 shows promise for heart failure

SY-5609 selected for development from novel selective CDK7 inhibitor series

COQ8B acts as a modifier of thoracic aortic aneurysm severity

Microbiome-derived butyrate builds bone

Giving herpesviruses a TRIM

How malaria drugs fight cancer

Assembly Biosciences initiates first-in-human study of ABI-H2158

Promentis Pharmaceuticals completes phase I studies of SXC-2023

Hummingbird Bioscience presents unique mechanism of action for novel anti-HER3 antibody

FDA grants approval for Adcetris as first-line treatment for peripheral T-cell lymphoma

Promacta granted FDA approval for first-line SAA and breakthrough therapy designation for H-ARS

Japanese researchers patent compounds for fibrosis

Takeda Pharmaceutical presents CaS antagonists

FDA approves Aemcolo for the treatment of travelers' diarrhea

FDA approves IND for first-in-human study of GZ17-6.02

Chemotherapeutic agents reactivate HBV via ribophorin II downregulation

Bridge Biotherapeutics files IND for BBT-877

Bifunctional agent N-809 demonstrates effective cancer immunotherapeutic properties

First patient enrolled in a phase III study of clonidine micropellet for sciatica

First results presented with RNAi ARO-HBV in chronic HBV infection

First phase II data presented for IL-22 agonist F-652 in patients with alcoholic hepatitis

Proteostasis Therapeutics patents mutant CFTR correctors

Merck KGaA and Pfizer provide update on JAVELIN ovarian cancer program of avelumab

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