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Home » Newsletters » BioWorld Science

BioWorld Science

Dec. 11, 2018

View Archived Issues

Targeting Mdf could inhibit the evolution of antimicrobial resistance

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Cation channel TRPV1 identified as a therapeutic target for cardiac hypertrophy and heart failure

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RIP1 is an immune checkpoint kinase conferring immunotherapy resistance in pancreatic ductal cancer

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BET bromodomain inhibitors destress ALS cells

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Alpha-synuclein derails lipid metabolism

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BCL6 unveiled as a novel therapeutic target for triple-negative breast cancer

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BRG1-SOX4 drives oncogenic signaling in triple-negative breast cancer

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CDC20 emerges as a novel target for triple-negative breast cancer

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Metastasis of triple-negative breast cancer is controlled by PEA15 phosphorylation

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In MDS and AML, many bad seeds

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Vanda presents promising data from pivotal study of tasimelteon in Smith-Magenis syndrome

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Phase II study of zilucoplan in gMG meets primary and key secondary endpoints

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Phase II study of serlopitant demonstrates reduction of pruritus associated with psoriasis

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Phase I study of silmitasertib shows promise in patients with cholangiocarcinoma

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Oppilan Pharma presents sphingosine 1-phosphate receptor 1 agonists

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LegoChem Biosciences patents E-NPP 2 inhibitors

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WDR5/MLL1 interaction inhibitors identified at the University of Michigan

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Prescient Therapeutics reports interim durability data on PTX-200 in breast cancer

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Vanderbilt University synthesizes RAS GTPase inhibitors

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Shionogi and Ube establish strategic research collaboration in RSV

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Arctic Pharma discovers lactate dehydrogenase A inhibitors

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Immix reports interim findings from phase Ib/IIa study of IMX-110 in advanced solid tumors

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Itanapraced demonstrates animal proof of concept in Parkinson's disease models

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Axovant reports exploratory phase II study results for nelotanserin

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Marinus reports interim phase II data with intravenous and oral ganaxolone in postpartum depression

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Constellation advances ProSTAR trial of CPI-1205 in metastatic CRPC into phase II

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IDMC recommends continuation of phase II/III trial of AXS-05 in Alzheimer's disease agitation

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Cantargia presents update on its CANFOUR study of CAN-04

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