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BioWorld Science

Dec. 27, 2018

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Dyanavel XR pharmacokinetics studied in younger pediatric population

Promising effects observed with JNJ-54175446 in major depressive disorder

UCM-924, a melatonin MT2 receptor agonist, shows promise for treating neuropathic pain

Portola Pharmaceuticals presents phase II data for cerdulatinib in patients with T-cell lymphoma

Cysteine protease ATG4B inhibitor LV-320 targets autophagy in leukemic cells

Researchers present new gene therapy for sickle cell anemia

Identification and evaluation of novel dual inhibitors of sodium-dependent glucose cotransporters

Otsuka opens enrollment in phase III trial of OPC-61815 for congestive heart failure

Momenta initiates phase II trial of M-281 in generalized myasthenia gravis

Alnylam Pharmaceuticals develops siRNA targeting the thrombopoietin gene in the liver

Novel CD38 CAR cell therapy for the treatment of multiple myeloma

Tumor-targeted trimeric 4-1BB-agonistic antibody 1D8N/CEGa1 shows safety and efficacy in vivo

ASO for LCA

New LAG-3 ligand identified

Oryzon patents lysine-specific demethylase inhibitors

NantBioScience reports high-affinity nerve growth factor receptor inhibitors

Shenzhen Salubris Pharmaceuticals describes DPP-IV inhibitors for diabetes

MEI Pharma initiates phase II study of ME-401 in follicular lymphoma

TRACON Pharmaceuticals submits IND application for TJ-4309

Mitophagy findings may offer new PD treatment promise

AbbVie licenses Lupin's MALT1 inhibitor program

Positive data presented from dose-escalation portion of phase I study of TRC-105

Sunshine Lake Pharma reports agents for the treatment of HBV infections

ROMK inhibitors reported in Bristol-Myers Squibb patent

Tyvyt approved in China for the treatment of Hodgkin's lymphoma

Capricor places voluntary hold on phase II HOPE-2 study of CAP-1002

FDA approves pediatric hexavalent combination vaccine Vaxelis

Arrowhead Pharmaceuticals initiates phase I study of ARO-ANG3

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