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Home » Newsletters » BioWorld Science

BioWorld Science

Dec. 17, 2018

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Discovery and characterization of novel spirocyclic sigma receptor ligands

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miR-335 delivery by extracellular vesicles restores tumor suppressor activity in breast cancer model

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Phase II data for ruxolitinib in PTCL and CTCL enriched for JAK/STAT pathway alterations

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Lilly initiates phase I study of LY-3454738 for atopic dermatitis

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Anergis completes proof-of-concept study of second-generation COP allergy vaccines

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XEN-901 shows promise in preclinical and first-in-human studies

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Synthetic astaxanthin derivative shows promise in the treatment of amyotrophic lateral sclerosis

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Takeda presents first-in-human data for TAK-653

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Eli Lilly presents phase II data from nextMONARCH 1 study

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Novel class of antibacterial compounds targeting the LPS transport system of Gram-negative bacteria

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CRISPR activation uses scissors as squeezers

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Axovant licenses gene therapies for GM1 and GM2 gangliosidosis from University of Massachusetts

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Vaximm initiates phase I/II study of VXM-01 plus avelumab for the treatment of glioblastoma

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Taiho Pharmaceutical divulges KDM1A inhibitors

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Gut bacteria eat, make neurotransmitter

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Oxford University Innovation presents bacterial beta-lactamase inhibitors

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Pfizer initiates phase III program for its 20-valent pneumococcal conjugate vaccine

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Suzhou Autopharm Biopharmaceutical synthesizes MAP1LC3B inhibitors

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Topadur Pharma discloses PDE5A inhibitors

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FDA approves Nplate for pediatric patients with immune thrombocytopenia

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Trastuzumab biosimilar Herzuma approved by FDA

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Janssen Pharmaceuticals and collaborator identify new antivirals for dengue

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Vedanta initiates phase II study of VE-303 for recurrent C. difficile infection

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FDA clears IND application for BBT-877 for IPF

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Valneva begins phase II with VLA-15 for Lyme disease

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DSMB recommends continuation of phase III RESOLVE-IT study of elafibranor in NASH

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C4X Discovery and Horizon Discovery establish target discovery partnership

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FDA approves Motegrity for adults with chronic idiopathic constipation

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Concert initiates phase I program with CTP-692 for adjunctive treatment of schizophrenia

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