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BioWorld Science

March 21, 2019

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Coming up for air

Vaxart initiates bivalent norovirus vaccine phase Ib study

Engineered protein can block "undruggable" oncogene

Alexion and Zealand Pharma collaborate to discover and develop novel peptide therapies

SOX2OT as a novel prognostic biomarker in bladder cancer

SIRS and hypoxemia in acute pancreatitis could be patient selection factors in studies of CM-4620

HSJ-633 prevents inflammation-induced preterm birth and fetal tissue injury in vivo

Aptevo initiates dosing in phase I study of APVO-210

Cancer gene therapy VB-111 has immunotherapeutic effects in resistant ovarian cancer

Ovarian cancer vaccine DCVAC/OvCa significantly improves survival in phase II trial

Hexima reports findings from second part of phase I/IIa onychomycosis study of HXP-124

Innovent initiates Chinese phase IIa study of IBI-306 for hypercholesterolemia

Knopp Biosciences enters collaboration to initiate phase II trial of dexpramipexole

Hangzhou Pulve Biotechnology describes chimeric antigen receptors targeting mesothelin

Chinese Academy of Sciences patents collagen-targeting VEGF

Merck & Co. identifies adenosine A2A and/or A2B receptor antagonists

Protein disulfide-isomerase inhibitors discovered at MUSC Foundation for Research Development

Genzada initiates phase I trial of GZ17-6.02 in advanced solid tumors and lymphoma

Vivace Therapeutics presents YAP1/TEAD interaction inhibitors

FDA approves Sunosi for excessive daytime sleepiness associated with narcolepsy or OSA

Genenta intiates phase I/II studies of Temferon in glioblastoma and multiple myeloma

First patient dosed in phase II RAIN-701 study of tarloxotinib in NSCLC

NapaJen, Astellas enter collaboration for development of novel oligonucleotides

Phase III ENGAGE and EMERGE studies of aducanumab in Alzheimer's to end based on futility analysis

Enterome announces collaboration with Dana-Farber on microbiome-derived cancer immunotherapy

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