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BioWorld Science

April 1, 2019

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MYRF gene mutations linked to the development of nanophthalmos

VNLG-152R shows promising antitumor and antimetastatic activity in models of TNBC

Mutations in ADAMTSL1 are responsible for the pathogenesis of mandibular prognathism

Antiviral etravirine increases frataxin levels: a potential therapy for Friedreich's ataxia

NB-360 improves memory deficit in mice

Rhythm Pharmaceuticals provides update on setmelanotide development program

Potent new glucocorticoid reverses severe steroid-resistant asthma

Proteo initiates clinical development of subcutaneous Elafin

MR-35602, a novel triple-activity compound with promising activity in model of AD

Merck & Co. presents novel AD-specific tau monoclonal antibody, MAFT-0617

Alpelisib plus olaparib demonstrates promising activity and safety in phase I study

XenoTherapeutics initiates phase I study of Xeno-Skin

Targeting hair loss outside the follicle

No pain, emotional gain due to newly identified mutation

BioThera Solutions recruiting participants in phase I study of BAT-8003

Immunic patents IFN-gamma and IL-17 production inhibitors

GlaxoSmithKline divulges new MYC, p300 and CREBBP inhibitors

Hutchison MediPharma identifies IDH inhibitors

Chiesi Farmaceutici presents ROCK1 and ROCK2 inhibitors

FDA approves Mavenclad for relapsing-remitting and active secondary progressive MS

Cancer vaccine iNeo-Vac-P01 safe and beneficial in patients with solid tumors

BeiGene discloses PI3Kdelta inhibitors

Auris announces randomization of first dose cohort in phase Ib study of AM-201

Actinium advances antibody radiation conjugate research program with Astellas

FDA approves Duaklir for maintenance treatment of COPD

Poxel initiates phase IIa NASH program with PXL-770

Phio and Glycostem explore synergies of technologies for cancer immunotherapy

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