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BioWorld - Monday, May 13, 2024
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BioWorld Science
April 2, 2019
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Indole-2-carboxamides show oral bioavailability and efficacy in M. abscessus-infected mice
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Missense mutation in SLC9A7 causes multigenerational nonsyndromic X-linked intellectual disability
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Tizona initiates phase I/Ib study of TTX-030 in advanced cancers
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Merck & Co. optimizes alpha7 nicotinic receptor PAM for cognitive disorders
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Antipsychotics target bacterial virulence factor
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PD biomarkers pass smell test
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Nemo stabilizes Tregs
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IDO1 heme antagonist GS-4361 is a potent and selective candidate
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AACR 2019: Clinical trials begin to solidify CAR T successes
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Potent, oral IAP antagonist TQB-3728 shows in vitro and in vivo antitumor activity
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Histone deacetylase inhibitor AES-135 shows preclinical efficacy against pancreatic cancer
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FDA issues complete response letter for midazolam nasal spray
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Bemcentinib plus low-dose cytarabine achieves efficacy endpoint in patients with AML
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Bristol-Myers Squibb presents hSTING agonists
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Recida initiates phase I study of LpxC inhibitor RC-01
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Symberix divulges GUS inhibitors for diarrhea
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Eli Lilly and Company disclose MAP3K5 inhibitors
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Incyte describes new MAP4K1 inhibitors
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TaiwanJ Pharmaceuticals divulges E-NPP 2 inhibitors
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Columbia University conducts exploratory evaluation of [11C]-NOP46 PET tracer for chronic pain
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Enrollment open in phase II study of bimiralisib for HNSCC with NOTCH1 LOF mutations
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European Commission approves Ajovy for migraine prophylaxis
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MediciNova reports subgroup analysis from phase IIb SPRINT-MS study of MN-166 in progressive MS
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Nanoliposomal ATR inhibitors presented for cancer therapy
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Asceniv approved by FDA to treat humoral immunodeficiency disease
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FDA approves reintroduction of Zelnorm
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