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BioWorld - Friday, April 19, 2024
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BioWorld Science
April 5, 2019
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Fate Therapeutics gives update on phase I study of FT-500
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Amgen identifies KRAS mutant inhibitors
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Entasis Therapeutics initiates global phase III ATTACK study of ETX-2514SUL
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First subject dosed in phase I study of SM-07883
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FDA clears IND application for phase I/II study of HMI-102 gene therapy candidate
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Patient recruitment ongoing in phase I study of TPST-1120
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Preclinical results for anti-HER2 TLR8 agonist conjugate for the treatment of HER2-expressing tumors
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Antigen transfer can induce CAR T friendly fire
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Promising preclinical data presented for the anti-CD39 antibody TTX-030
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Bayer reports phase I results for BAY-1125976
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Mkrn3 gene overexpression in mice generates model of delayed puberty
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K-975 shows strong antitumor effect in preclinical models of malignant pleural mesothelioma
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Chung-Ang University patents new compounds for cartilage regeneration
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Acceleron discontinues development of systemic muscle agent ACE-2494
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Merck & Co. presents new antibacterials
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Multi-peptide Top2A vaccine for immunoprevention of triple-negative breast cancer
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5MP1 role in pancreatic cancer progression: potential prognostic biomarker and therapeutic target
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Genentech and Roche identify anti-Gram-negative bacterial compounds
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Anti-BSP fused to CPPs shows antimetastatic potential in preclinical breast cancer models
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Metformin has beneficial effects in Alzheimer's disease model
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Small-molecule PD-L1 inhibitor MAX-10181 shows similar antitumor efficacy to durvalumab in mice
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SIMM describes bile acid receptor antagonists
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New phase I trial explores use of UB-221 for chronic spontaneous urticaria
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Phase I microdose study of radiolabeled PL-8177 meets primary and secondary endpoints
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Merrimack discontinues development of MM-310 owing to cumulative peripheral neuropathy in phase I
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FDA approves Ibrance to treat men with HR-positive, HER-negative breast cancer
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