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BioWorld Science

April 11, 2019

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Diversion is novel way of enzyme inhibition

Potassium promotes T-cell stemness

New model to trial schizophrenia preventative treatments

FDA accepts IND application for first-in-human study of PSB-205

Galapagos initiates first-in-human trial of GLPG-3121

U.S. researchers present a 5-HT2A receptor inhibitor antibody

Merck & Co. identifies new nicotinic alpha-7 receptor positive allosteric modulators

CCDC102B is strongly correlated with negative clinical outcome in breast cancer

Menin/MLL interaction inhibitors discovered at Kura Oncology

Kymera Therapeutics discovers protein cereblon inhibitors

ESSA Pharmaceuticals presents the characterization of next-generation Anitens

Leo Pharma patents phosphodiesterase PDE4D inhibitors

ABM Therapeutics presents V600E mutant raf kinase B inhibitors

Phase Ib/II data presented for DV-281 in combination with nivolumab in patients with NSCLC

New and potent IDO1 inhibitors from Merck & Co. presented

I-Mab Biopharma collaborates with Roche on clinical study of TJD-5 with Tecentriq

Alkeus begins phase III study of ALK-001 for GA secondary to AMD

Sanaria announces agreements to support development of PfSPZ vaccine for malaria

AstraZeneca DNA-PK inhibitor AZD-7648 has single-agent and combination antitumor activity

New phase I trial evaluates AVID-200 in patients with myelofibrosis

Evotec and Indivumed to use IndivuType database for colorectal cancer drug discovery

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