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BioWorld - Sunday, December 7, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

April 26, 2019

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Opioids impervious to GLP-1 agonists

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Unexpected role of reduced myelination in Williams syndrome

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Missense mutation in myoglobin causes an adult-onset autosomal dominant myopathy

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STELLAR-3 study of selonsertib does not meet prespecified week 48 primary endpoint

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Janssen initiates phase I study of JNJ-67571244 in patients with AML or MDS

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Allegro Ophthalmics names new anti-integrin product for dry eye disease

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EDP-514 demonstrates potent preclinical antiviral activity

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CYFRA 21-1 as novel prognostic marker in advanced liver disease

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ANGPTL2 knockdown results in mouse model of spontaneous aortic valve stenosis

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Tachykinin NK1 receptor antagonists suppress leukemic cell growth

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Kezar Life Sciences presents new compounds with antitumoral activity

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DOC2A Ca2+ sensor is overexpressed in temporal lobe epilepsy in humans and rat models

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OMPTA agent POL-7306 is potent against Gram-negative bacteria in vitro and in vivo

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GlaxoSmithKline patents new HBV inhibitors

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Takeda presents JAK inhibitors

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hSTING modulators disclosed in GlaxoSmithKline patent

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Takeda identifies glutamate receptor agonists

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Structure, activity described for AMG-510, the first-in-human covalent inhibitor of KRAS G12C

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University of Miami presents new compositions for epidermolysis bullosa

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FDA approves Duobrii for plaque psoriasis

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Pimavanserin begins phase III for major depressive disorder

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ReNeuron reports new data from phase I/IIa study of hRPC therapy candidate for retinitis pigmentosa

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Japanese phase III study of delgocitinib in pediatric atopic dermatitis meets primary endpoint

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Novartis describes activity in vivo of TLR7 agonist LHC-165, now entering phase I

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NIH to send 3-D tissue chips into space to study aging and diseases accelerated in microgravity

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