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BioWorld - Wednesday, April 24, 2024
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BioWorld Science
May 2, 2019
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Safety and efficacy of autologous gene therapy after busulfan conditioning in infants with SCID-X1
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Pharmacological modulation of sigma 2 receptor shows in vivo neuroprotective effect after TBI
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Development of a new animal model of acute-on-chronic liver failure
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TCF20 deficiency tied to liver fibrosis in animal models
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Trigger region found for absence epileptic seizures
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Discovery and optimization of novel STING agonist for the treatment of cancer
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UCB-9260 demonstrates promising activity in TNF-alpha-driven mouse model
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First patient enrolled in proof-of-concept study of ATH-3G10 in heart failure
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FDA lifts partial clinical hold on phase I study of XmAb-14045
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Phase IIa study of BIV-201 in refractory ascites meets primary objectives
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Preclinical results presented for Ad5-3M in the treatment of solid and disseminated tumors
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Gel-B prevents hepatic steatosis in HFD-induced NAFLD in vivo
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Soluble MAdCAM-1 as a novel marker of endothelial activation in decompensated cirrhosis
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Exonate presents SRPK1 inhibitor EXN-407
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Innovatives Molecules describes new antiviral compounds
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FORMA Therapeutics identifies new histone deacetylase 6 inhibitors
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New phase II trial investigates BPN-14770 in early Alzheimer's disease
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FDA approves Dengvaxia for prevention of dengue infection in endemic areas
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Shanghai Institute of Materia Medica discloses new antibacterials
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Bristol-Myers Squibb patents IDO-1 inhibitors
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Merck & Co. describes new LRRK2 inhibitors
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MCT 4 lactate transporter inhibitor AZD-0095 targets immunosuppression in tumors
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NexImmune and MMRF partner to advance NEXI-002 for multiple myeloma
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Genkyotex reports topline phase II data for GKT-831 in primary biliary cholangitis
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FDA issues complete response letter for HTX-011 for postoperative pain
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Checkpoint Therapeutics reports interim data from phase I trial of cosibelimab
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FDA approves Mavyret for pediatric patients with HCV
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European Commission approves Skyrizi for plaque psoriasis
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Phase I study of CVN-424 for Parkinson's demonstrates safety in healthy subjects
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Kalydeco approved in U.S. for infants from 6 months with cystic fibrosis
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FDA issues complete response letter for Contepo for complicated urinary tract infections
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3-V Biosciences initiates phase II trial of TVB-2640 in NASH
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