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BioWorld Science

May 17, 2019

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Tumor stem cells need much methionine

Medivir presents phase II results for topical remetinostat in basal cell carcinoma

Preclinical evaluation of CWHM-1008 as an antimalarial agent

Varicella virus-specific T cells expressing GD2 CAR safe with vaccine in osteosarcoma patients

Cellular-systemic iron link is therapeutic target for overload disorders

European Commission approves Revlimid and Imnovid-based triplet regimens for multiple myeloma

Vasopressin V2 receptor antagonists disclosed by Toa Eiyo

Bayer, Dana-Farber Cancer Institute and The Broad Institute patent mutant EGFR inhibitors

Researchers present updated data from SUNFISH study on risdiplam for SMA

Chronos Therapeutics presents orexin OX1 and/or OX2 receptor antagonists

Suven Life Sciences identifies muscarinic M1 receptor positive allosteric modulators

Enrollment open in phase III study of fostamatinib in warm antibody autoimmune hemolytic anemia

Esteve Pharmaceuticals presents dual CACNA2D1/NET ligands

Small molecule OCX-063 protects against experimental diabetic retinopathy

FDA lifts partial clinical hold on phase III AIM2CERV trial of axalimogene filolisbac

FDA clinical hold lifted from second cohort of ADVM-022 in phase I trial for wet AMD

FDA accepts Cue's IND for first-in-human trial of CUE-101 for HPV-associated cancers

CDH11 is a predictor of unfavorable prognosis in gastric cancer

PEP-Therapy completes GLP toxicity studies for PEP-010

Deinove eyes start of phase II trial with DNV-3837 for C. difficile infection

uniQure generates AAV5 vector FIX variant gene therapy for hemophilia A

First patient dosed in study of AXO-AAV-GM1 gene therapy for GM1 gangliosidosis

Proof of concept achieved for KB-103 as topical treatment for epidermolysis bullosa dystrophica

Achillion presents interim data from phase II trial of ACH-4471 with eculizumab in PNH

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