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BioWorld Science

June 7, 2019

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Aqualung Therapeutics wins award to support development of therapies for ARDS

In vitro study identifies factors responsible for the SPARCL of youth

AMG-172 investigated in relapsed/refractory renal cell carcinoma

Axovant presents 6-month follow-up data from first cohort of SUNRISE-PD study

Enlivex Therapeutics provides clinical update for its OTS Allocetra therapy for severe sepsis

Early signals of clinical activity observed in phase I study of KX2-391 in patients with psoriasis

TAXIS Pharmaceuticals identifies new antibacterials

Principia Biopharma patents proteasome subunit beta type-8 and/or beta type-9 inhibitors

The University of Kansas, Victoria Link disclose mu-opioid receptor agonists

Bristol-Myers Squibb presents Toll-like receptor 7, 8 and/or 9 antagonists

MAP3K5 inhibitors discovered at Sidecar Therapeutics

Apalutamide + ADT in mCSPC: first data from the TITAN study presented

Nasally administered olanzapine INP-105 more rapidly absorbed than other formulations

Phase III ASCERTAIN trial of ASTX-727 in MDS or CMML meets primary endpoint

Purdue initiates phase I study of nalmefene hydrochloride for emergency treatment of opioid overdose

Goldfinch begins first-in-human study of GFB-887 for kidney disease

NeRRe reports data from phase IIb study of orvepitant in chronic cough

Novartis presents data from LINC3 study on osilodrostat in patients with Cushing's disease

American BriVision reports phase II data on ABV-1504 for major depressive disorder

Anti-ENG antibody-drug conjugates show preclinical efficacy for the treatment of Ewing's sarcoma

Identification and characterization of a fluorinated indole-imidazole as a 5-HT7 receptor agonist

Novel berberine-metformin hybrid with improved antihyperlipidemic effect for type 2 diabetes

Phase I results presented for ERK-1/2 inhibitor LY-3214996 in advanced cancer

Preliminary activity seen with estrogen receptor alpha antagonist H3B-6545 in breast cancer

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