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BioWorld Science

June 13, 2019

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STAT6 siRNA sequences induce apoptosis and proliferation inhibition in colorectal/breast cancer

XMT-1536 well tolerated in phase I study in patients with solid tumors likely to express NaPi2b

First-in-human data presented for enapotamab vedotin in patients with advanced cancer

The BiTE immune-oncology therapeutic pasotuxizumab shows promising efficacy in mCRPC

Elderly cells found in regenerating organs

Kinase boost could be strategy for Lewy body busting

SCO-267, a novel GPR40 full agonist, improves glucose control in rats

Safety and efficacy of AB-BNCT in recurrent and locally advanced head and neck cancer

Phase I/IIa study of GEN-009 neoantigen vaccine containing autologous stimulatory peptides

Increased CCL14 expression linked to chronic kidney disease

Drug vulnerabilities due to tumor suppressor loss assayed

Alkermes initiates monotherapy expansion phase of ARTISTRY-1 study of ALKS-4230

ABBV-085 demonstrates manageable safety and preliminary activity in patients with sarcoma

Preliminary data presented from first-in-human study of AZD-5153

Genentech presents phase II data on fenebrutinib for rheumatoid arthritis with inadequate response

Daiichi Sankyo divulges GLP-1 receptor agonists

Roche patents gamma-secretase inhibitors

GemVax & KAEL presents new TGF-beta inhibitors and TNF production inhibitors

Pharvaris describes bradykinin B2 receptor antagonists

Dart NeuroScience synthesizes new PDE1B inhibitors

Topline data from phase III study of Molgradex in autoimmune alveolar pulmonary proteinosis

Phase IIa study of ALLOB used in lumbar spinal fusion procedure meets primary endpoints

Phase II study of Lyme disease vaccine candidate VLA-15 enters main study phase

IDMC recommends continuation of phase III study of masitinib in pancreatic cancer

IMV announces updated phase II findings for DPX-Survivac in DLBCL

Allele Biotechnology and Alpine BioTherapeutics enter research agreement on iPSCs for vision loss

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