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BioWorld Science

June 17, 2019

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mRNA-based vaccine elicits neoantigen specific T-cell responses in common epithelial cancers

Genentech initiates phase II study of RO-7171009 in geographic atrophy secondary to AMD

Recruitment ongoing in phase I study of NNC0268-0965

Phase Ib/II data presented for ralimetinib in combination with chemotherapy in ovarian cancer

New phase Ib trial studies gevokizumab for metastatic colorectal, gastroesophageal and renal cancers

Phase I study to assess DDO-3055 in healthy volunteers and patients with chronic kidney disease

Celgene initiates phase I study of CC-92252

EDP-938 achieves primary and secondary endpoints in phase IIa human challenge study

Phase III SANET-ep study of surufatinib meets primary endpoint at interim analysis

AMG-510 demonstrates safety and preliminary antitumor activity in KRAS G12C mutant tumors

5F9 shows promising safety and activity both as monotherapy and in combination with azacitidine

Phase I/II data reported for CPX-351 in pediatric patients with relapsed AML

Autolus describes cells comprisnig CARs or or T-cell receptors and a beta2-microglobulin ectodomain

Okayama University patents 89Zr-labeled scFv targeting human mesothelin compositions

Janssen Biotech patents human umbilical cord tissue-derived cells

First phase II data presented for Imago's IMG-7899 in myelofibrosis

EHA 2019: AWOL microbiome cells rile up blood stem cells

CRISPR without DNA breaks

New oncolytic viruses presented by Kagoshima University

Hiroshima University, 3-D Matrix present anticancer microRNAs

Emapalumab proven efficacious in sJIA patients with MAS/HLH

Krystal files IND for first-in-human study of KB-105 for autosomal recessive congenital ichthyosis

TLC reports data from part 1 of phase II bunionectomy trial of TLC-590

Elthera receives funding through E.U.'s Horizon 2020 program

Extracellular vesicles deliver antiaging enzyme

Antibody-antibiotic conjugate DSTA-4637S well tolerated in phase I study

Telaglenastat doubles PFS in heavily pretreated patients with advanced RCC in ENTRATA trial

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