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BioWorld Science

July 3, 2019

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Neutrophils have antitumor effects, can improve clinical outcomes

Endogenous retrovirus has link to MS

MS-1768 acts as a specific dopamine D2 receptor partial agonist

Novel zebrafish model to study the role of STUB1 in ataxia

Dicerna to initiate clinical development of DCR-A1AT for A1AT deficiency-associated liver disease

FDA grants IND approval for phase I/II study of anti-Fc gamma RllB antibody

ANT-2681 demonstrates pH-dependent potency and in vitro antibacterial activity

First clinical efficacy and safety data for 225Ac-DOTATATE in GEP-NET

Strong immunoprotection with a Zika VLP vaccine in a murine model

PPNA-40: comparable activity to tigecycline in multidrug-resistant A. baumannii model

MediSynergics divulges compounds for parasitic diseases

Daiichi Sankyo discloses new EP300 and/or CBP inhibitors

Basilea Pharmaceutica patent describes mitochondrial inhibitors

Leo Pharma describes PDE4 and TNF-alpha release inhibitors

IDO1 inhibitors reported in Phenex Discovery Verwaltungs patent

Low-dose mercury causes heart failure in mice

Data reported from first-in-human ATB200-02 trial of ATB-200/AT-2221 combination in Pompe disease

Appili Therapeutics to advance antibiotic program

FDA places clinical hold on phase I trial of ACTR-087 for relapsed/refractory NHL

Phase III MINISTONE-2 study of Xofluza in children with influenza meets primary endpoint

Tracon advances phase I/II trial of androgen receptor antagonist TRC-253 in metastatic CRPC

European Commission approves Dovato for HIV-1 infection

Algernon's NP-120 reduces fibrosis in in vivo animal model study of IPF

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