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BioWorld Science

July 17, 2019

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'CYRI, prevent that infection!'

Finding MDS' iron fist

New platform optimizes genome-editing enzyme activity

Ambrx announces initiation of phase I study of a long-acting relaxin

Novartis publishes first-in-human data for LYS-228

AMG-424 demonstrates promising activity in preclinical models of multiple myeloma

Teplizumab delays progression to clinical type 1 diabetes in relatives at risk

SAD study data on the anti-phospho-tau antibody JNJ-63733657 in healthy subjects presented

SHANK3-mutant macaque with altered connectivity and behavior as a model of autism spectrum disorder

PBD-C06: development candidate for immunotherapy against Alzheimer's disease

Druggability Technologies begins phase II trial of DRGT-119 for chronic anal fissure

Sichuan Kelun-Biotech Biopharmaceutical describes bile acid receptor agonists

mTORC1/mTORC2 inhibitor MTI-31 shows promise for treating lung cancer

Merck & Co. identifies PI3Kdelta inhibitors

Chiesi Farmaceutici divulges Rho kinase inhibitors

Boehringer Ingelheim patents SOS1 inhibitors

STING is required to restrict MCMV dissemination to lymph nodes

Bristol-Myers Squibb presents Toll-like receptor antagonists

Skyhawk and Genentech to discover and develop small-molecule RNA splicing modifiers

Affibody completes 12-week interim analysis of phase II psoriasis study of ABY-035

MDA funding supports development of small-molecule drugs to increase sarcospan expression for DMD

Mallinckrodt discontinues phase IIb study of Acthar gel in ALS

Researchers in search of small-molecule NAMPT activators for Alzheimer's disease

FDA clears investigator-initiated phase II trial of GKT-831 for IPF

Cyclica and University of Toronto enter EGFR inhibitor collaboration

FDA approves Recarbrio for complicated urinary tract and intra-abdominal infections

Invio cuts select early R&D programs to focus on HPV-related diseases

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