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BioWorld Science

July 30, 2019

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Masitinib can slow the functional decline in ALS patients

Next-generation IL-10-based therapeutic with tumor-targeted delivery prevents CD8+ T-cell apoptosis

PK and PD of GSK-2292767A, a novel low-solubility inhaled phosphoinositide 3-kinase delta inhibitor

Selective CaMKII inhibition by gene therapy suppresses arrhythmias in CPVT models

Radioluminescent nanoparticle system allows for radiation-controlled release of chemotherapies

Alterity Therapeutics completes phase I study of PBT-434

FDA accepts IND application for CERC-802 for the treatment of MPI deficiency

Spring Bank receives FDA acceptance of IND application for intravenous SB-11285

Novel GLUT-4 translocation enhancers discoverd as potential therapeutic agents for diabetes mellitus

First-in-human results for two novel monovalent oral type 2 poliovirus vaccine candidates

CD19-BBz(86) anti-CD19 CAR T-cell therapy demonstrates safety and efficacy in phase I study

SHH signaling modulation as a promising new therapeutic strategy for ECO syndrome

BMP pathway blockade is a potential therapeutic approach for osteoarthritis

Roche divulges new MGL inhibitors

Allinky Biopharma identifies GTPase KRAS inhibitors

Medshine Discovery presents CXCR2 antagonists

Aurigene Discovery Technologies describes CD47 antagonists

Much bias, little binary: in sex differences in gene expression, "the whole genome is in the game"

Galecto Biotech identifies Gal-1 and Gal-3 inhibitors

4D presents new preclinical data on Live Biotherapeutic oncology programs

Microbiome metabolites modulate ALS

Biodesix and Immodulon Therapeutics collaborate on biomarker research for IMM-101

VBI advances phase I/IIa study of VBI-1901 for recurrent GBM into part B

Phase IIa study of AKST-4290 in refractory wet AMD meets primary endpoint

FDA clears Hepion's IND application to study CRV-431 for NASH

InterveXion reports interim data from phase II study of IXT-m200 for methamphetamine use disorder

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