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BioWorld - Monday, March 16, 2026
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BioWorld Science
Aug. 1, 2019
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Novel bis-indole-derived NR4A1 antagonists inhibit breast cancer cell growth in vitro and in vivo
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Development of a new class of indazole-based MRA by modern CH functionalization chemistry
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Microbiome metabolites modulate neonatal asthma risk
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Zinc finger RNA binding protein found to be potent oncogene in colorectal and liver cancers
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OXPHOS-dependent population of poor outcome AML can be targeted with the ERBB2 inhibitor mubritinib
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Excell Biotech advances HSV vaccine EXD-12 through preclinical testing
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PSLNR, an androgen-receptor prostate-specific lncRNA, is involved in prostate cancer progression
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CARB-X funds BB100 to develop a unique monoclonal antibody against E. coli infection
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FDA grants approval for new monotherapy indication for Keytruda
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Turning Point Therapeutics initiates phase I clinical study of TPX-0022
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Jaktinib demonstrates promising safety and PK in healthy volunteers
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Developmental biliary agenesis in ALGS is reversible via restoration of Jagged/Notch
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Researchers investigate dose optimization for levornidazole
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Kymera Therapeutics patents CRBN inhibitors
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Sage Therapeutics identifies new GABA-A receptor modulators
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Medshine Discovery presents KRAS mutant inhibitors
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New phase II trial studies IPI-549 with nivolumab in advanced urothelial carcinoma
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IND open for phase II study of ELX-02 in cystic fibrosis
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Roche synthesizes gamma-secretase inhibitors
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MannKind advances pediatric study of Afrezza into final cohort
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DSMB recommends continuation of phase II study of ANAVEX 2-73 for Rett syndrome
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Sichuan Kelun-Biotech Biopharmaceutical describes IDO1 inhibitors
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Aronora opens phase II study of AB-002 in end-stage renal disease patients on chronic hemodialysis
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Sickle cell disease: Editing small group of cells leads to big-enough effects
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